Hilft eine Kombination aus einem Dopaminagonisten (Domperidon) und einem Sympathomimietikum (Pseudoephedrin) zur Behandlung der obstruktiven Schlafapnoe? 23 Patienten mit einem Desaturationsindex (H\u00c3\u00a4ufigkeit der Sauerstoffents\u00c3\u00a4ttigungen pro Stunde) zwischen 6,1 und 112,4\/h erhielten die Medikationskombination. Es wurde \u00c3\u00bcber weniger Schnarchen und eine Besserung von Tagesschl\u00c3\u00a4frigkeit berichtet.\u00c2\u00a0 Die Anzahl der Ents\u00c3\u00a4ttigungen nahm teils deutlich, teils kaum ab. Insgesamt ist die Studie zwar interessant, hat ebr erhebliche Schw\u00c3\u00a4chen. Genauer als die Messung des Desaturationsindex w\u00c3\u00a4ren Ergebnisse einer Polygraphie, besser noch Polysomnographie. Auch wurden alle Patienten zu sehr unterschiedlichen Zeiten nachuntersuch, zwischen einem und 12 Monaten. Auch fehlt der Plazeboversuch. Es gibt also noch viele unklare Punkte, bevor mehr zu dieser Medikation gesagt werden kann. Zum jetzigen Zeitpunkt kann die Kombination nicht empfohlen werden.\u00c2\u00a0 (Larrain A et al. J Clin Sleep Med 2010;6:117-123)<\/p>\n","protected":false},"excerpt":{"rendered":"
Hilft eine Kombination aus einem Dopaminagonisten (Domperidon) und einem Sympathomimietikum (Pseudoephedrin) zur Behandlung der obstruktiven Schlafapnoe? 23 Patienten mit einem Desaturationsindex (H\u00c3\u00a4ufigkeit der Sauerstoffents\u00c3\u00a4ttigungen pro Stunde) zwischen 6,1 und 112,4\/h erhielten die Medikationskombination. Es wurde \u00c3\u00bcber weniger Schnarchen und eine Besserung von Tagesschl\u00c3\u00a4frigkeit berichtet.\u00c2\u00a0 Die Anzahl der Ents\u00c3\u00a4ttigungen nahm teils deutlich, teils kaum ab. Insgesamt […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-371","post","type-post","status-publish","format-standard","hentry","category-allgemein"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"hein","author_link":"https:\/\/dr-holger-hein.de\/reloaded\/author\/hein\/"},"uagb_comment_info":0,"uagb_excerpt":"Hilft eine Kombination aus einem Dopaminagonisten (Domperidon) und einem Sympathomimietikum (Pseudoephedrin) zur Behandlung der obstruktiven Schlafapnoe? 23 Patienten mit einem Desaturationsindex (H\u00c3\u00a4ufigkeit der Sauerstoffents\u00c3\u00a4ttigungen pro Stunde) zwischen 6,1 und 112,4\/h erhielten die Medikationskombination. Es wurde \u00c3\u00bcber weniger Schnarchen und eine Besserung von Tagesschl\u00c3\u00a4frigkeit berichtet.\u00c2\u00a0 Die Anzahl der Ents\u00c3\u00a4ttigungen nahm teils deutlich, teils kaum ab. Insgesamt…","_links":{"self":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/posts\/371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/comments?post=371"}],"version-history":[{"count":0,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/posts\/371\/revisions"}],"wp:attachment":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/media?parent=371"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/categories?post=371"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/tags?post=371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}