Ein metabolisches Syndrom (hoher Blutdruck, hohe Blutfette\/Cholesterinwerte, Insulinresistenz, Fettleibigkeit im Bauchbereich) haben etwa ¾ aller Patienten mit obstruktiver Schlafapnoe. Bei 86 Patienten mit Schlafapnoe im Alter von im Mittel 45 Jahren und einem Body-Mass-Index von im Mittel 32 kg\/m\u00c2\u00b2 wurden Me\u00c3\u0178werte eines metabolischen Syndroms (Blutdruck, N\u00c3\u00bcchternblutzucker, Insulinresistenz, Blutfette, HbA1, Intima-Media-Dicke der Aa. carotes, Bauchfett) nach jeweils 3 Wochen CPAP-Therapie mit effektivem Druck und nach 3 Wochen mit zu niedrigem Druck (=Placebo) ermittelt. Ein effektiver Druck f\u00c3\u00bchrte zu im Mittel 3,9 mmHg geringeren systolischen und 2,5 mmHg niedrigeren diastolischen Blutdruckwerten, das LDL-Cholsterin war 9,6 mg\/dl vermindert, die Triglyzeride lagen 18,7 mg\/dl niedriger, und das HbA1 fiel um 0,2%. Unter effektivem CPAP erf\u00c3\u00bcllten 1% der Patienten (1 von 86) die Kriterien des metabolischen Syndroms, unter Placebo-CPAP aber 13% (11 von 86). Sharma SK et al. New Engl J Med 2011;365:2277-2286<\/p>\n","protected":false},"excerpt":{"rendered":"
Ein metabolisches Syndrom (hoher Blutdruck, hohe Blutfette\/Cholesterinwerte, Insulinresistenz, Fettleibigkeit im Bauchbereich) haben etwa ¾ aller Patienten mit obstruktiver Schlafapnoe. Bei 86 Patienten mit Schlafapnoe im Alter von im Mittel 45 Jahren und einem Body-Mass-Index von im Mittel 32 kg\/m\u00c2\u00b2 wurden Me\u00c3\u0178werte eines metabolischen Syndroms (Blutdruck, N\u00c3\u00bcchternblutzucker, Insulinresistenz, Blutfette, HbA1, Intima-Media-Dicke der Aa. carotes, Bauchfett) nach […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-326","post","type-post","status-publish","format-standard","hentry","category-allgemein"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"hein","author_link":"https:\/\/dr-holger-hein.de\/reloaded\/author\/hein\/"},"uagb_comment_info":0,"uagb_excerpt":"Ein metabolisches Syndrom (hoher Blutdruck, hohe Blutfette\/Cholesterinwerte, Insulinresistenz, Fettleibigkeit im Bauchbereich) haben etwa ¾ aller Patienten mit obstruktiver Schlafapnoe. Bei 86 Patienten mit Schlafapnoe im Alter von im Mittel 45 Jahren und einem Body-Mass-Index von im Mittel 32 kg\/m\u00c2\u00b2 wurden Me\u00c3\u0178werte eines metabolischen Syndroms (Blutdruck, N\u00c3\u00bcchternblutzucker, Insulinresistenz, Blutfette, HbA1, Intima-Media-Dicke der Aa. carotes, Bauchfett) nach…","_links":{"self":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/posts\/326","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/comments?post=326"}],"version-history":[{"count":0,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/posts\/326\/revisions"}],"wp:attachment":[{"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/media?parent=326"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/categories?post=326"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dr-holger-hein.de\/reloaded\/wp-json\/wp\/v2\/tags?post=326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}